Course Title : Chemical Biology

Code 71290
Course Year 3rd year
Term
Class day & Period
Location
Credits 2
Restriction No Restriction
Lecture Form(s) Lecture
Language Japanese
Instructor Tabata and Yamamoto (Inst. for Frontier Med. Sci.),

Course Description

It is important in the field of life science to understand biochemistry and biological medicine in terms of organic material chemistry. The way to think and view the biological system and bioprocess at the molecular level can make clear the academic knowledge of life science and contribute to the development of engineering-medicine-pharmacy interdisciplinary research area. In this lecture, proteins, polysaccharides, and lipids of bio-related substances as well as cells, cell membrane, extracellular matrix of biological system are explained in terms of chemical biology. As a representative of engineering-medicine-pharmacy interdisciplinary research area, drug delivery system (DDS) and regenerative medicine are introduced. In addition, some topics in the field of life science, including stem cells, body defense and immunology, and endocrine disruptor, are also covered.

Grading

The credit is judged by the scheduled examination and the attendant rate.

Course Goals

The objective of the lecture is to obtain the fundamental knowledge of proteins, polysaccharides, lipids, cells, and extracellular matrix and understand stem cells, body defense, DDS, regenerative medicine, and endocrine disruptor of life science application.

Course Topics

Theme Class number of times Description
Proteins and enzymes 2 Structure and function of proteins and enzymes
Polysaccharides and lipids 1 Structure and function of polysaccharides and lipids
Cell and cell membrane 1 Structure and function of cells and membrane transportation
Signal transduction 1 Signal transduction at cell membrane
Energy conversion 1 Oxidative phosphorylation to generate ATP
Cytoskeleton 1 Cellular biomechanics and biochemistry of cytoskeleton
Body defense and immunology 1 System and function of body defense and immunology
Stem cells 1 System, function, and medical application of stem cells
Cell and extracellular matrix 1 Structure and function of extracellular matrix
Regenerative medicine and material science 2 Overview of regenerative medicine based on material science
Drug delivery system (DDS) 1 Overview of DDS based on material science
Endocrine disruptor 1 Overview of endocrine disruptor based on material science
Achievement evaluation 1 Credit evaluation based on the understanding level of lecture contents

Textbook

Textbook(supplemental)

Fundamentals of Biochemistry: Life at the Molecular Level;Wiley
Molecular biology of the Cell ;Garland Science
ますます重要になる細胞周辺環境(細胞ニッチ)の最新科学技術;株式会社メディカルドゥ
Immunology;Saunders
生物薬剤学;株式会社南江堂
絵で見てわかるナノDDS;株式会社メディカルドゥ

Prerequisite(s)

Web Sites

Additional Information